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Nimodipine-loaded mixed micelles: formulation, compatibility, pharmacokinetics, and vascular irritability study

BACKGROUND: The clinical application of nimodipine (NIM) is limited by several unfavorable properties, which are induced by its low aqueous solubility. In the present study, nimodipine-loaded egg phosphatidylcholine-sodium glycocholate mixed micelles (NIM-EPC-SGC-MMs) were prepared to improve the wa...

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Detalles Bibliográficos
Autores principales:	Song, Xu, Jiang, Yu, Ren, Chunjuan, Sun, Xun, Zhang, Qiang, Gong, Tao, Zhang, Zhirong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414212/ https://www.ncbi.nlm.nih.gov/pubmed/22888228 http://dx.doi.org/10.2147/IJN.S33228

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