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Enhanced apoptosis of ovarian cancer cells via nanocarrier-mediated codelivery of siRNA and doxorubicin

A folate conjugated ternary copolymer, FA–PEG–PEI–PCL, of poly(ethylene glycol) (PEG), poly(ethylene imine) (PEI), and poly(ɛ-caprolactone) (PCL) was synthesized. The copolymer self-assembled into cationic micelles capable of co-delivering siRNA and the anticancer drug doxorubicin (DOX). This dual f...

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Detalles Bibliográficos
Autores principales:	Zou, Seyin, Cao, Nuo, Cheng, Du, Zheng, Rongqin, Wang, Jin, Zhu, Kangshun, Shuai, Xintao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414222/ https://www.ncbi.nlm.nih.gov/pubmed/22888237 http://dx.doi.org/10.2147/IJN.S29328

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