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Nanoemulsion liquid preconcentrates for raloxifene hydrochloride: optimization and in vivo appraisal
Raloxifene hydrochloride (RLX) is a selective estrogen-receptor modulator for treatment of osteoporosis and prevention of breast and endometrial cancer. By virtue of extensive presystemic clearance, RLX bioavailability is only 2%. The current study aimed to tailor and characterize RLX-loaded self-na...
Autores principales: | Elsheikh, Manal A, Elnaggar, Yosra SR, Gohar, Eman Y, Abdallah, Ossama Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414224/ https://www.ncbi.nlm.nih.gov/pubmed/22888234 http://dx.doi.org/10.2147/IJN.S33186 |
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