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Genetic contribution to radiographic severity in osteoarthritis of the knee

OBJECTIVE: Knee osteoarthritis (OA) has a significant genetic component. The authors have assessed the role of three variants reported to influence risk of knee OA with p<5×10–8 in determining patellofemoral and tibiofemoral Kellgren Lawrence (K/L) grade in knee OA cases. METHODS: 3474 knee OA ca...

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Detalles Bibliográficos
Autores principales:	Valdes, Ana M, Doherty, Sally, Muir, Kenneth R, Zhang, Weiya, Maciewicz, Rose A, Wheeler, Margaret, Arden, Nigel, Cooper, Cyrus, Doherty, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Group 2012
Materias:	Clinical and Epidemiological Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414227/ https://www.ncbi.nlm.nih.gov/pubmed/22615457 http://dx.doi.org/10.1136/annrheumdis-2012-201382

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