40-De­oxy-40(S)-iodo­rapamycin

The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra­molecular O—H⋯O inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Lijun, Zuo, Jian, Yang, Guoxin, Zheng, Congshen, Cheng, Yuanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414270/
https://www.ncbi.nlm.nih.gov/pubmed/22904803
http://dx.doi.org/10.1107/S1600536812027547
Descripción
Sumario:The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra­molecular O—H⋯O inter­action also occurs.

Ejemplares similares