40-De­oxy-40(S)-iodo­rapamycin

The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra­molecular O—H⋯O inter...

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Detalles Bibliográficos
Autores principales: Xie, Lijun, Zuo, Jian, Yang, Guoxin, Zheng, Congshen, Cheng, Yuanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414270/
https://www.ncbi.nlm.nih.gov/pubmed/22904803
http://dx.doi.org/10.1107/S1600536812027547
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author Xie, Lijun
Zuo, Jian
Yang, Guoxin
Zheng, Congshen
Cheng, Yuanrong
author_facet Xie, Lijun
Zuo, Jian
Yang, Guoxin
Zheng, Congshen
Cheng, Yuanrong
author_sort Xie, Lijun
collection PubMed
description The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra­molecular O—H⋯O inter­action also occurs.
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spelling pubmed-34142702012-08-17 40-De­oxy-40(S)-iodo­rapamycin Xie, Lijun Zuo, Jian Yang, Guoxin Zheng, Congshen Cheng, Yuanrong Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra­molecular O—H⋯O inter­action also occurs. International Union of Crystallography 2012-07-04 /pmc/articles/PMC3414270/ /pubmed/22904803 http://dx.doi.org/10.1107/S1600536812027547 Text en © Xie et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Xie, Lijun
Zuo, Jian
Yang, Guoxin
Zheng, Congshen
Cheng, Yuanrong
40-De­oxy-40(S)-iodo­rapamycin
title 40-De­oxy-40(S)-iodo­rapamycin
title_full 40-De­oxy-40(S)-iodo­rapamycin
title_fullStr 40-De­oxy-40(S)-iodo­rapamycin
title_full_unstemmed 40-De­oxy-40(S)-iodo­rapamycin
title_short 40-De­oxy-40(S)-iodo­rapamycin
title_sort 40-de­oxy-40(s)-iodo­rapamycin
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414270/
https://www.ncbi.nlm.nih.gov/pubmed/22904803
http://dx.doi.org/10.1107/S1600536812027547
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AT zuojian 40deoxy40siodorapamycin
AT yangguoxin 40deoxy40siodorapamycin
AT zhengcongshen 40deoxy40siodorapamycin
AT chengyuanrong 40deoxy40siodorapamycin

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