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(E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide

The title compound, C(20)H(23)BrN(2)O(2), containing an ibuprofen core, crystallizes with three independent mol­ecules of similar conformation in the asymmetric unit. In these three mol­ecules, the two benzene rings make dihedral angles of 82.7 (2), 71.2 (2) and 78.0 (3)° with respect to each other....

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Detalles Bibliográficos
Autores principales: Mohamed, Shaaban K., Horton, Peter N., Akkurt, Mehmet, Albayati, Mustafa R., Abdelhamid, Antar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414297/
https://www.ncbi.nlm.nih.gov/pubmed/22904830
http://dx.doi.org/10.1107/S1600536812030322
Descripción
Sumario:The title compound, C(20)H(23)BrN(2)O(2), containing an ibuprofen core, crystallizes with three independent mol­ecules of similar conformation in the asymmetric unit. In these three mol­ecules, the two benzene rings make dihedral angles of 82.7 (2), 71.2 (2) and 78.0 (3)° with respect to each other. The atoms of the isobutyl groups in two of the mol­ecules are disordered over two positions, with site-occupancy ratios of 0.516 (8):0.484 (8) and 0.580 (8):0.420 (8). In the crystal, mol­ecules are linked by N—H⋯O, C—H⋯O and O—H⋯N hydrogen bonds. Furthermore, C—H⋯π inter­actions are also observed.