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(E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide

The title compound, C(20)H(23)BrN(2)O(2), containing an ibuprofen core, crystallizes with three independent mol­ecules of similar conformation in the asymmetric unit. In these three mol­ecules, the two benzene rings make dihedral angles of 82.7 (2), 71.2 (2) and 78.0 (3)° with respect to each other....

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Autores principales: Mohamed, Shaaban K., Horton, Peter N., Akkurt, Mehmet, Albayati, Mustafa R., Abdelhamid, Antar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414297/
https://www.ncbi.nlm.nih.gov/pubmed/22904830
http://dx.doi.org/10.1107/S1600536812030322
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author Mohamed, Shaaban K.
Horton, Peter N.
Akkurt, Mehmet
Albayati, Mustafa R.
Abdelhamid, Antar A.
author_facet Mohamed, Shaaban K.
Horton, Peter N.
Akkurt, Mehmet
Albayati, Mustafa R.
Abdelhamid, Antar A.
author_sort Mohamed, Shaaban K.
collection PubMed
description The title compound, C(20)H(23)BrN(2)O(2), containing an ibuprofen core, crystallizes with three independent mol­ecules of similar conformation in the asymmetric unit. In these three mol­ecules, the two benzene rings make dihedral angles of 82.7 (2), 71.2 (2) and 78.0 (3)° with respect to each other. The atoms of the isobutyl groups in two of the mol­ecules are disordered over two positions, with site-occupancy ratios of 0.516 (8):0.484 (8) and 0.580 (8):0.420 (8). In the crystal, mol­ecules are linked by N—H⋯O, C—H⋯O and O—H⋯N hydrogen bonds. Furthermore, C—H⋯π inter­actions are also observed.
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spelling pubmed-34142972012-08-17 (E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide Mohamed, Shaaban K. Horton, Peter N. Akkurt, Mehmet Albayati, Mustafa R. Abdelhamid, Antar A. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(20)H(23)BrN(2)O(2), containing an ibuprofen core, crystallizes with three independent mol­ecules of similar conformation in the asymmetric unit. In these three mol­ecules, the two benzene rings make dihedral angles of 82.7 (2), 71.2 (2) and 78.0 (3)° with respect to each other. The atoms of the isobutyl groups in two of the mol­ecules are disordered over two positions, with site-occupancy ratios of 0.516 (8):0.484 (8) and 0.580 (8):0.420 (8). In the crystal, mol­ecules are linked by N—H⋯O, C—H⋯O and O—H⋯N hydrogen bonds. Furthermore, C—H⋯π inter­actions are also observed. International Union of Crystallography 2012-07-07 /pmc/articles/PMC3414297/ /pubmed/22904830 http://dx.doi.org/10.1107/S1600536812030322 Text en © Mohamed et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Mohamed, Shaaban K.
Horton, Peter N.
Akkurt, Mehmet
Albayati, Mustafa R.
Abdelhamid, Antar A.
(E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide
title (E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide
title_full (E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide
title_fullStr (E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide
title_full_unstemmed (E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide
title_short (E)-N′-(5-Bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide
title_sort (e)-n′-(5-bromo-2-hy­droxy­benzyl­idene)-2-(4-isobutyl­phen­yl)propano­hydrazide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414297/
https://www.ncbi.nlm.nih.gov/pubmed/22904830
http://dx.doi.org/10.1107/S1600536812030322
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