(S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one

In the title compound, C(21)H(17)N(3)O(3), the dihydro­quinazoline ring adopts a screw-boat conformation and its stereogenic C atom has an S configuration. The dihedral angle between the mean planes of the two hy­droxy­phenyl rings is 86.61 (12)°. The amino H atom forms an intra­molecular hydrogen b...

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Autores principales: Tinguiano, Daniel, Sy, Adama, Thiam, Ibrahima Elhadj, Gaye, Mohamed, Retailleau, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414304/
https://www.ncbi.nlm.nih.gov/pubmed/22904837
http://dx.doi.org/10.1107/S1600536812030012
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author Tinguiano, Daniel
Sy, Adama
Thiam, Ibrahima Elhadj
Gaye, Mohamed
Retailleau, Pascal
author_facet Tinguiano, Daniel
Sy, Adama
Thiam, Ibrahima Elhadj
Gaye, Mohamed
Retailleau, Pascal
author_sort Tinguiano, Daniel
collection PubMed
description In the title compound, C(21)H(17)N(3)O(3), the dihydro­quinazoline ring adopts a screw-boat conformation and its stereogenic C atom has an S configuration. The dihedral angle between the mean planes of the two hy­droxy­phenyl rings is 86.61 (12)°. The amino H atom forms an intra­molecular hydrogen bond with a phenol O atom, while the hydrazine N atom acts as an acceptor for the H atom of the other phenol group. In the crystal, O—H⋯N and O—H⋯O hydrogen bonds and weak C—H⋯centroid(π-ring) inter­molecular inter­actions are observed, forming chains along [1-10] and [110].
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spelling pubmed-34143042012-08-17 (S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one Tinguiano, Daniel Sy, Adama Thiam, Ibrahima Elhadj Gaye, Mohamed Retailleau, Pascal Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(21)H(17)N(3)O(3), the dihydro­quinazoline ring adopts a screw-boat conformation and its stereogenic C atom has an S configuration. The dihedral angle between the mean planes of the two hy­droxy­phenyl rings is 86.61 (12)°. The amino H atom forms an intra­molecular hydrogen bond with a phenol O atom, while the hydrazine N atom acts as an acceptor for the H atom of the other phenol group. In the crystal, O—H⋯N and O—H⋯O hydrogen bonds and weak C—H⋯centroid(π-ring) inter­molecular inter­actions are observed, forming chains along [1-10] and [110]. International Union of Crystallography 2012-07-07 /pmc/articles/PMC3414304/ /pubmed/22904837 http://dx.doi.org/10.1107/S1600536812030012 Text en © Tinguiano et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Tinguiano, Daniel
Sy, Adama
Thiam, Ibrahima Elhadj
Gaye, Mohamed
Retailleau, Pascal
(S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one
title (S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one
title_full (S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one
title_fullStr (S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one
title_full_unstemmed (S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one
title_short (S,E)-3-[(2-Hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1H)-one
title_sort (s,e)-3-[(2-hy­droxy­benzyl­idene)amino]-2-(2-hy­droxy­phen­yl)-2,3-dihydro­quinazolin-4(1h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414304/
https://www.ncbi.nlm.nih.gov/pubmed/22904837
http://dx.doi.org/10.1107/S1600536812030012
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