4-{[7-(Trifluoro­meth­yl)quinolin-4-yl]amino}­benzene­sulfonamide–ethanol–methanol (1/0.47/0.53)

In the title compound, C(16)H(12)F(3)N(3)O(2)S·0.47C(2)H(5)OH·0.53CH(3)OH, the quinoline ring system is approximately planar, with a maximum deviation of 0.035 (3) Å, and makes a dihedral angle of 52.67 (9)° with the benzene ring. The F atoms of the –CF(3) group are disordered over two orientations,...

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Detalles Bibliográficos
Autores principales: Ghorab, Mostafa M., Al-Said, Mansour S., Al-Mishari, Abdullah A., Quah, Ching Kheng, Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414320/
https://www.ncbi.nlm.nih.gov/pubmed/22904853
http://dx.doi.org/10.1107/S1600536812029698
Descripción
Sumario:In the title compound, C(16)H(12)F(3)N(3)O(2)S·0.47C(2)H(5)OH·0.53CH(3)OH, the quinoline ring system is approximately planar, with a maximum deviation of 0.035 (3) Å, and makes a dihedral angle of 52.67 (9)° with the benzene ring. The F atoms of the –CF(3) group are disordered over two orientations, with refined site occupancies of 0.56 (2) and 0.44 (2). A single solvate site is occupied at random by ethanol or methanol, with refined site occupancies of 0.470 (6) and 0.530 (6), respectively. In the crystal, mol­ecules are linked via N—H⋯O, N—H⋯N, O—H⋯O and C—H⋯O hydrogen bonds, thereby forming sheets lying parallel to (010).

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