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Dimethyl 2-[24-acetyl-28-oxo-8,11,14-trioxa-24,27-diaza­penta­cyclo­[19.5.1.1(22,26).0(2,7).0(15,20)]octa­cosa-2,4,6,15(20),16,18-hexaen-27-yl]but-2-enedioate

The title compound, C(31)H(34)N(2)O(9), is a product of the Michael addition of the cyclic secondary amine subunit of the (bis­pidino)aza-14-crown-4 ether to dimethyl acetyl­ene­dicarboxyl­ate. The mol­ecule comprises a tricyclic system containing the aza-14-crown-3 ether macrocycle and two six-memb...

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Detalles Bibliográficos
Autores principales: Hieu, Truong Hong, Anh, Le Tuan, Soldatenkov, Anatoly T., Kolyadina, Nadezhda M., Khrustalev, Victor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414347/
https://www.ncbi.nlm.nih.gov/pubmed/22904880
http://dx.doi.org/10.1107/S1600536812030644
Descripción
Sumario:The title compound, C(31)H(34)N(2)O(9), is a product of the Michael addition of the cyclic secondary amine subunit of the (bis­pidino)aza-14-crown-4 ether to dimethyl acetyl­ene­dicarboxyl­ate. The mol­ecule comprises a tricyclic system containing the aza-14-crown-3 ether macrocycle and two six-membered piperidinone rings. The aza-14-crown-3-ether ring adopts a bowl conformation with a dihedral angle between the planes of the fused benzene rings of 51.14 (5)°. The central piperidone ring has a boat conformation, whereas the terminal piperidone ring adopts a chair conformation. The dimethyl ethyl­enedicarboxyl­ate fragment has a cis configuration with a dihedral angle of 56.56 (7)° between the two carboxyl­ate groups. The crystal packing is stabilized by weak C—H⋯O hydrogen bonds.