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PML body meets telomere: The beginning of an ALTernate ending?

The unlimited proliferation potential of cancer cells requires the maintenance of their telomeres. This is frequently accomplished by reactivation of telomerase. However, in a significant fraction of tumors an alternative lengthening of telomeres (ALT) mechanism is active. The molecular mechanism of...

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Detalles Bibliográficos
Autores principales:	Chung, Inn, Osterwald, Sarah, Deeg, Katharina I., Rippe, Karsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414403/ https://www.ncbi.nlm.nih.gov/pubmed/22572954 http://dx.doi.org/10.4161/nucl.20326

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