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Predicting HLA Class I Non-Permissive Amino Acid Residues Substitutions
Prediction of peptide binding to human leukocyte antigen (HLA) molecules is essential to a wide range of clinical entities from vaccine design to stem cell transplant compatibility. Here we present a new structure-based methodology that applies robust computational tools to model peptide-HLA (p-HLA)...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414483/ https://www.ncbi.nlm.nih.gov/pubmed/22905104 http://dx.doi.org/10.1371/journal.pone.0041710 |