Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome

BACKGROUND: Normal post-squalene cholesterol biosynthesis is important for mammalian embryonic development. Neonatal mice lacking functional dehydrocholesterol Δ7-reductase (Dhcr7), a model for the human disease of Smith-Lemli-Opitz syndrome, die within 24 hours of birth. Although they have a number...

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Detalles Bibliográficos
Autores principales: Yu, Hongwei, Wessels, Andy, Chen, Jianliang, Phelps, Aimee L, Oatis, John, Tint, G Stephen, Patel, Shailendra B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC341451/
https://www.ncbi.nlm.nih.gov/pubmed/15005800
http://dx.doi.org/10.1186/1471-213X-4-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC341451/
https://www.ncbi.nlm.nih.gov/pubmed/15005800
http://dx.doi.org/10.1186/1471-213X-4-1

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