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A patient with primary Burkitt’s lymphoma of the postnasal space: case report
INTRODUCTION: Burkitt’s lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burki...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414781/ https://www.ncbi.nlm.nih.gov/pubmed/22695293 http://dx.doi.org/10.1186/1758-3284-4-33 |
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author | Upile, Tahwinder Jerjes, Waseem Abiola, Jesuloba Kafas, Panagiotis Sandison, Ann Hamdoon, Zaid Al-Khawalde, Mohammed Radhi, Hani |
author_facet | Upile, Tahwinder Jerjes, Waseem Abiola, Jesuloba Kafas, Panagiotis Sandison, Ann Hamdoon, Zaid Al-Khawalde, Mohammed Radhi, Hani |
author_sort | Upile, Tahwinder |
collection | PubMed |
description | INTRODUCTION: Burkitt’s lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burkitt’s lymphoma of the postnasal space occurring in an elderly Caucasian male. CASE PRESENTATION: A 72-year-old Caucasian male farmer presented with a 6-week history of a productive cough and a painless left sided cervical swelling. Examination of the neck revealed a 5 cm by 5 cm hard mass in the left anterior triangle. A CT scan of the head and neck showed a soft tissue swelling in the postnasal space. Histology of the postnasal space mass showed squamous mucosa infiltrated by a high grade lymphoma. Immunohistochemical staining and in situ hybridisation confirmed the tumour to be Epstein - Barr virus Ribonucleic acid negative suggesting this was a rare sporadic form of the tumour presenting in a location that is atypical for the clinical subtype and age of the patient. CONCLUSION: This is the first reported case of sporadic Burkitt’s lymphoma of the postnasal space of an elderly Caucasian male in the absence of Epstein - Barr virus or human immunodeficiency virus infection and further serves to illustrate the diversity of histological subtypes of malignancies that may develop at this concealed site. |
format | Online Article Text |
id | pubmed-3414781 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34147812012-08-10 A patient with primary Burkitt’s lymphoma of the postnasal space: case report Upile, Tahwinder Jerjes, Waseem Abiola, Jesuloba Kafas, Panagiotis Sandison, Ann Hamdoon, Zaid Al-Khawalde, Mohammed Radhi, Hani Head Neck Oncol Case Report INTRODUCTION: Burkitt’s lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burkitt’s lymphoma of the postnasal space occurring in an elderly Caucasian male. CASE PRESENTATION: A 72-year-old Caucasian male farmer presented with a 6-week history of a productive cough and a painless left sided cervical swelling. Examination of the neck revealed a 5 cm by 5 cm hard mass in the left anterior triangle. A CT scan of the head and neck showed a soft tissue swelling in the postnasal space. Histology of the postnasal space mass showed squamous mucosa infiltrated by a high grade lymphoma. Immunohistochemical staining and in situ hybridisation confirmed the tumour to be Epstein - Barr virus Ribonucleic acid negative suggesting this was a rare sporadic form of the tumour presenting in a location that is atypical for the clinical subtype and age of the patient. CONCLUSION: This is the first reported case of sporadic Burkitt’s lymphoma of the postnasal space of an elderly Caucasian male in the absence of Epstein - Barr virus or human immunodeficiency virus infection and further serves to illustrate the diversity of histological subtypes of malignancies that may develop at this concealed site. BioMed Central 2012-06-13 /pmc/articles/PMC3414781/ /pubmed/22695293 http://dx.doi.org/10.1186/1758-3284-4-33 Text en Copyright © 2012 Upile et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Upile, Tahwinder Jerjes, Waseem Abiola, Jesuloba Kafas, Panagiotis Sandison, Ann Hamdoon, Zaid Al-Khawalde, Mohammed Radhi, Hani A patient with primary Burkitt’s lymphoma of the postnasal space: case report |
title | A patient with primary Burkitt’s lymphoma of the postnasal space: case report |
title_full | A patient with primary Burkitt’s lymphoma of the postnasal space: case report |
title_fullStr | A patient with primary Burkitt’s lymphoma of the postnasal space: case report |
title_full_unstemmed | A patient with primary Burkitt’s lymphoma of the postnasal space: case report |
title_short | A patient with primary Burkitt’s lymphoma of the postnasal space: case report |
title_sort | patient with primary burkitt’s lymphoma of the postnasal space: case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414781/ https://www.ncbi.nlm.nih.gov/pubmed/22695293 http://dx.doi.org/10.1186/1758-3284-4-33 |
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