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A patient with primary Burkitt’s lymphoma of the postnasal space: case report

INTRODUCTION: Burkitt’s lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burki...

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Autores principales: Upile, Tahwinder, Jerjes, Waseem, Abiola, Jesuloba, Kafas, Panagiotis, Sandison, Ann, Hamdoon, Zaid, Al-Khawalde, Mohammed, Radhi, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414781/
https://www.ncbi.nlm.nih.gov/pubmed/22695293
http://dx.doi.org/10.1186/1758-3284-4-33
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author Upile, Tahwinder
Jerjes, Waseem
Abiola, Jesuloba
Kafas, Panagiotis
Sandison, Ann
Hamdoon, Zaid
Al-Khawalde, Mohammed
Radhi, Hani
author_facet Upile, Tahwinder
Jerjes, Waseem
Abiola, Jesuloba
Kafas, Panagiotis
Sandison, Ann
Hamdoon, Zaid
Al-Khawalde, Mohammed
Radhi, Hani
author_sort Upile, Tahwinder
collection PubMed
description INTRODUCTION: Burkitt’s lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burkitt’s lymphoma of the postnasal space occurring in an elderly Caucasian male. CASE PRESENTATION: A 72-year-old Caucasian male farmer presented with a 6-week history of a productive cough and a painless left sided cervical swelling. Examination of the neck revealed a 5 cm by 5 cm hard mass in the left anterior triangle. A CT scan of the head and neck showed a soft tissue swelling in the postnasal space. Histology of the postnasal space mass showed squamous mucosa infiltrated by a high grade lymphoma. Immunohistochemical staining and in situ hybridisation confirmed the tumour to be Epstein - Barr virus Ribonucleic acid negative suggesting this was a rare sporadic form of the tumour presenting in a location that is atypical for the clinical subtype and age of the patient. CONCLUSION: This is the first reported case of sporadic Burkitt’s lymphoma of the postnasal space of an elderly Caucasian male in the absence of Epstein - Barr virus or human immunodeficiency virus infection and further serves to illustrate the diversity of histological subtypes of malignancies that may develop at this concealed site.
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spelling pubmed-34147812012-08-10 A patient with primary Burkitt’s lymphoma of the postnasal space: case report Upile, Tahwinder Jerjes, Waseem Abiola, Jesuloba Kafas, Panagiotis Sandison, Ann Hamdoon, Zaid Al-Khawalde, Mohammed Radhi, Hani Head Neck Oncol Case Report INTRODUCTION: Burkitt’s lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burkitt’s lymphoma of the postnasal space occurring in an elderly Caucasian male. CASE PRESENTATION: A 72-year-old Caucasian male farmer presented with a 6-week history of a productive cough and a painless left sided cervical swelling. Examination of the neck revealed a 5 cm by 5 cm hard mass in the left anterior triangle. A CT scan of the head and neck showed a soft tissue swelling in the postnasal space. Histology of the postnasal space mass showed squamous mucosa infiltrated by a high grade lymphoma. Immunohistochemical staining and in situ hybridisation confirmed the tumour to be Epstein - Barr virus Ribonucleic acid negative suggesting this was a rare sporadic form of the tumour presenting in a location that is atypical for the clinical subtype and age of the patient. CONCLUSION: This is the first reported case of sporadic Burkitt’s lymphoma of the postnasal space of an elderly Caucasian male in the absence of Epstein - Barr virus or human immunodeficiency virus infection and further serves to illustrate the diversity of histological subtypes of malignancies that may develop at this concealed site. BioMed Central 2012-06-13 /pmc/articles/PMC3414781/ /pubmed/22695293 http://dx.doi.org/10.1186/1758-3284-4-33 Text en Copyright © 2012 Upile et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Upile, Tahwinder
Jerjes, Waseem
Abiola, Jesuloba
Kafas, Panagiotis
Sandison, Ann
Hamdoon, Zaid
Al-Khawalde, Mohammed
Radhi, Hani
A patient with primary Burkitt’s lymphoma of the postnasal space: case report
title A patient with primary Burkitt’s lymphoma of the postnasal space: case report
title_full A patient with primary Burkitt’s lymphoma of the postnasal space: case report
title_fullStr A patient with primary Burkitt’s lymphoma of the postnasal space: case report
title_full_unstemmed A patient with primary Burkitt’s lymphoma of the postnasal space: case report
title_short A patient with primary Burkitt’s lymphoma of the postnasal space: case report
title_sort patient with primary burkitt’s lymphoma of the postnasal space: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414781/
https://www.ncbi.nlm.nih.gov/pubmed/22695293
http://dx.doi.org/10.1186/1758-3284-4-33
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