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Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans

BACKGROUND: Severe alcohol misuse as measured by the Alcohol Use Disorders Identification Test–Consumption (AUDIT-C) is associated with increased risk of future fractures and trauma-related hospitalizations. This study examined the association between AUDIT-C scores and two-year risk of any type of...

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Autores principales: Harris, Alex H S, Lembke, Anna, Henderson, Patricia, Gupta, Shalini, Moos, Rudolf, Bradley, Katharine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414833/
https://www.ncbi.nlm.nih.gov/pubmed/22966411
http://dx.doi.org/10.1186/1940-0640-7-6
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author Harris, Alex H S
Lembke, Anna
Henderson, Patricia
Gupta, Shalini
Moos, Rudolf
Bradley, Katharine A
author_facet Harris, Alex H S
Lembke, Anna
Henderson, Patricia
Gupta, Shalini
Moos, Rudolf
Bradley, Katharine A
author_sort Harris, Alex H S
collection PubMed
description BACKGROUND: Severe alcohol misuse as measured by the Alcohol Use Disorders Identification Test–Consumption (AUDIT-C) is associated with increased risk of future fractures and trauma-related hospitalizations. This study examined the association between AUDIT-C scores and two-year risk of any type of trauma among US Veterans Health Administration (VHA) patients and assessed whether risk varied by age or gender. METHODS: Outpatients (215, 924 male and 9168 female) who returned mailed AUDIT-C questionnaires were followed for 24 months in the medical record for any International Statistical Classification of Diseases and Related Health Problems (ICD-9) code related to trauma. The two-year prevalence of trauma was examined as a function of AUDIT-C scores, with low-level drinking (AUDIT-C 1–4) as the reference group. Men and women were examined separately, and age-stratified analyses were performed. RESULTS: Having an AUDIT-C score of 9–12 (indicating severe alcohol misuse) was associated with increased risk for trauma. Mean (SD) ages for men and women were 68.2 (11.5) and 57.2 (15.8), respectively. Age-stratified analyses showed that, for men ≤50 years, those with AUDIT-C scores ≥9 had an increased risk for trauma compared with those with AUDIT-C scores in the 1–4 range (adjusted prevalence, 25.7% versus 20.8%, respectively; OR = 1.24; 95% confidence interval [CI], 1.03–1.50). For men ≥65 years with average comorbidity and education, those with AUDIT-C scores of 5–8 (adjusted prevalence, 7.9% versus 7.4%; OR = 1.16; 95% CI, 1.02–1.31) and 9–12 (adjusted prevalence 11.1% versus 7.4%; OR = 1.68; 95% CI, 1.30–2.17) were at significantly increased risk for trauma compared with men ≥65 years in the reference group. Higher AUDIT-C scores were not associated with increased risk of trauma among women. CONCLUSIONS: Men with severe alcohol misuse (AUDIT-C 9–12) demonstrate an increased risk of trauma. Men ≥65 showed an increased risk for trauma at all levels of alcohol misuse (AUDIT-C 5–8 and 9–12). These findings may be used as part of an evidence-based brief intervention for alcohol use disorders. More research is needed to understand the relationship between AUDIT-C scores and risk of trauma in women.
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spelling pubmed-34148332012-09-11 Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans Harris, Alex H S Lembke, Anna Henderson, Patricia Gupta, Shalini Moos, Rudolf Bradley, Katharine A Addict Sci Clin Pract Research BACKGROUND: Severe alcohol misuse as measured by the Alcohol Use Disorders Identification Test–Consumption (AUDIT-C) is associated with increased risk of future fractures and trauma-related hospitalizations. This study examined the association between AUDIT-C scores and two-year risk of any type of trauma among US Veterans Health Administration (VHA) patients and assessed whether risk varied by age or gender. METHODS: Outpatients (215, 924 male and 9168 female) who returned mailed AUDIT-C questionnaires were followed for 24 months in the medical record for any International Statistical Classification of Diseases and Related Health Problems (ICD-9) code related to trauma. The two-year prevalence of trauma was examined as a function of AUDIT-C scores, with low-level drinking (AUDIT-C 1–4) as the reference group. Men and women were examined separately, and age-stratified analyses were performed. RESULTS: Having an AUDIT-C score of 9–12 (indicating severe alcohol misuse) was associated with increased risk for trauma. Mean (SD) ages for men and women were 68.2 (11.5) and 57.2 (15.8), respectively. Age-stratified analyses showed that, for men ≤50 years, those with AUDIT-C scores ≥9 had an increased risk for trauma compared with those with AUDIT-C scores in the 1–4 range (adjusted prevalence, 25.7% versus 20.8%, respectively; OR = 1.24; 95% confidence interval [CI], 1.03–1.50). For men ≥65 years with average comorbidity and education, those with AUDIT-C scores of 5–8 (adjusted prevalence, 7.9% versus 7.4%; OR = 1.16; 95% CI, 1.02–1.31) and 9–12 (adjusted prevalence 11.1% versus 7.4%; OR = 1.68; 95% CI, 1.30–2.17) were at significantly increased risk for trauma compared with men ≥65 years in the reference group. Higher AUDIT-C scores were not associated with increased risk of trauma among women. CONCLUSIONS: Men with severe alcohol misuse (AUDIT-C 9–12) demonstrate an increased risk of trauma. Men ≥65 showed an increased risk for trauma at all levels of alcohol misuse (AUDIT-C 5–8 and 9–12). These findings may be used as part of an evidence-based brief intervention for alcohol use disorders. More research is needed to understand the relationship between AUDIT-C scores and risk of trauma in women. BioMed Central 2012 2012-04-30 /pmc/articles/PMC3414833/ /pubmed/22966411 http://dx.doi.org/10.1186/1940-0640-7-6 Text en Copyright ©2012 Harris et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Harris, Alex H S
Lembke, Anna
Henderson, Patricia
Gupta, Shalini
Moos, Rudolf
Bradley, Katharine A
Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans
title Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans
title_full Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans
title_fullStr Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans
title_full_unstemmed Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans
title_short Risk of future trauma based on alcohol screening scores: A two-year prospective cohort study among US veterans
title_sort risk of future trauma based on alcohol screening scores: a two-year prospective cohort study among us veterans
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414833/
https://www.ncbi.nlm.nih.gov/pubmed/22966411
http://dx.doi.org/10.1186/1940-0640-7-6
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