Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish (Danio rerio) larvae but not Daphnia magna

Organic solvents, such as dimethylsulfoxide (DMSO) and methanol are widely used as vehicles to solubilise lipophilic test compounds in toxicity testing. However, the effects of such solvents upon innate detoxification processes in aquatic organisms are poorly understood. This study assessed the effe...

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Detalles Bibliográficos
Autores principales: David, Rhiannon M., Jones, Huw S., Panter, Grace H., Winter, Matthew J., Hutchinson, Thomas H., Kevin Chipman, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414850/
https://www.ncbi.nlm.nih.gov/pubmed/22472102
http://dx.doi.org/10.1016/j.chemosphere.2012.03.018

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