Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate

The title compound, C(21)H(26)N(2)O(5), was unexpectedly obtained as a by-product in the reaction of ethyl acetoacetate, 4-acetamido­benzaldehyde and urea under microwave irradiation. The dihydro­pyridine ring assumes a flattened boat conformation. Inter­molecular N—H⋯O and weak C—H⋯O hydrogen bondi...

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Detalles Bibliográficos
Autores principales: Zhao, Yiliang, Hibbs, David E., Groundwater, Paul W., Wassef, Abram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414982/
https://www.ncbi.nlm.nih.gov/pubmed/22904969
http://dx.doi.org/10.1107/S160053681202750X
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author Zhao, Yiliang
Hibbs, David E.
Groundwater, Paul W.
Wassef, Abram
author_facet Zhao, Yiliang
Hibbs, David E.
Groundwater, Paul W.
Wassef, Abram
author_sort Zhao, Yiliang
collection PubMed
description The title compound, C(21)H(26)N(2)O(5), was unexpectedly obtained as a by-product in the reaction of ethyl acetoacetate, 4-acetamido­benzaldehyde and urea under microwave irradiation. The dihydro­pyridine ring assumes a flattened boat conformation. Inter­molecular N—H⋯O and weak C—H⋯O hydrogen bonding occurs in the crystal.
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spelling pubmed-34149822012-08-17 Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate Zhao, Yiliang Hibbs, David E. Groundwater, Paul W. Wassef, Abram Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(21)H(26)N(2)O(5), was unexpectedly obtained as a by-product in the reaction of ethyl acetoacetate, 4-acetamido­benzaldehyde and urea under microwave irradiation. The dihydro­pyridine ring assumes a flattened boat conformation. Inter­molecular N—H⋯O and weak C—H⋯O hydrogen bonding occurs in the crystal. International Union of Crystallography 2012-07-25 /pmc/articles/PMC3414982/ /pubmed/22904969 http://dx.doi.org/10.1107/S160053681202750X Text en © Zhao et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhao, Yiliang
Hibbs, David E.
Groundwater, Paul W.
Wassef, Abram
Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_full Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_fullStr Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_full_unstemmed Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_short Diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_sort diethyl 4-(4-acetamido­phenyl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414982/
https://www.ncbi.nlm.nih.gov/pubmed/22904969
http://dx.doi.org/10.1107/S160053681202750X
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