(2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol

The title compound, C(14)H(19)NO(5)S, was prepared by nucleophilic addition of the lithium derivative of methyl­phenyl­sulfone to (3S,4R)-3,4-isopropyl­idene­dioxy­pyrroline 1-oxide. There are four mol­ecules in the asymmetric unit. The crystal structure determination confirms the configuration of t...

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Detalles Bibliográficos
Autores principales: Flores, Mari Fe, Garcia, Pilar, M. Garrido, Narciso, Sanz, Francisca, Diez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415002/
https://www.ncbi.nlm.nih.gov/pubmed/22904989
http://dx.doi.org/10.1107/S1600536812033028
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author Flores, Mari Fe
Garcia, Pilar
M. Garrido, Narciso
Sanz, Francisca
Diez, David
author_facet Flores, Mari Fe
Garcia, Pilar
M. Garrido, Narciso
Sanz, Francisca
Diez, David
author_sort Flores, Mari Fe
collection PubMed
description The title compound, C(14)H(19)NO(5)S, was prepared by nucleophilic addition of the lithium derivative of methyl­phenyl­sulfone to (3S,4R)-3,4-isopropyl­idene­dioxy­pyrroline 1-oxide. There are four mol­ecules in the asymmetric unit. The crystal structure determination confirms the configuration of the chiral centres as 2R,3S,4R. In the crystal, pairs of O—H⋯N hydrogen bonds link the mol­ecules into dimers.
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spelling pubmed-34150022012-08-17 (2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol Flores, Mari Fe Garcia, Pilar M. Garrido, Narciso Sanz, Francisca Diez, David Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(14)H(19)NO(5)S, was prepared by nucleophilic addition of the lithium derivative of methyl­phenyl­sulfone to (3S,4R)-3,4-isopropyl­idene­dioxy­pyrroline 1-oxide. There are four mol­ecules in the asymmetric unit. The crystal structure determination confirms the configuration of the chiral centres as 2R,3S,4R. In the crystal, pairs of O—H⋯N hydrogen bonds link the mol­ecules into dimers. International Union of Crystallography 2012-07-28 /pmc/articles/PMC3415002/ /pubmed/22904989 http://dx.doi.org/10.1107/S1600536812033028 Text en © Flores et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Flores, Mari Fe
Garcia, Pilar
M. Garrido, Narciso
Sanz, Francisca
Diez, David
(2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol
title (2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol
title_full (2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol
title_fullStr (2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol
title_full_unstemmed (2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol
title_short (2R,3S,4R)-3,4-Isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol
title_sort (2r,3s,4r)-3,4-isopropyl­idenedi­oxy-2-(phenyl­sulfonyl­meth­yl)pyrrolidin-1-ol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415002/
https://www.ncbi.nlm.nih.gov/pubmed/22904989
http://dx.doi.org/10.1107/S1600536812033028
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