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Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns
Purpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchan...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415089/ https://www.ncbi.nlm.nih.gov/pubmed/22900218 http://dx.doi.org/10.1155/2012/864958 |
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author | Mota, Ágata Fonseca, Sofia Carneiro, Ângela Magalhães, Augusto Brandão, Elisete Falcão-Reis, Fernando |
author_facet | Mota, Ágata Fonseca, Sofia Carneiro, Ângela Magalhães, Augusto Brandão, Elisete Falcão-Reis, Fernando |
author_sort | Mota, Ágata |
collection | PubMed |
description | Purpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchanged for years. Results. In the first case, spectral-domain optical coherence tomography (SD-OCT) showed reduced foveal pit and continuity of inner retinal layers in the fovea. Photoreceptor layer had a normal thickness centrally. The foveal avascular zone (FAZ) was absent in the flourescein angiogram (FA). Fundus autofluorescence showed reduced foveal attenuation of autofluorescence. In the second patient, there was the same pattern in SD-OCT, with normal aspect in FA and only a slightly reduced foveal attenuation of autofluorescence. Conclusion. OCT, as a noninvasive and quick method, is helpful in the diagnosis of foveal hypoplasia. FA and fundus autofluorescence were less sensitive. |
format | Online Article Text |
id | pubmed-3415089 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-34150892012-08-16 Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns Mota, Ágata Fonseca, Sofia Carneiro, Ângela Magalhães, Augusto Brandão, Elisete Falcão-Reis, Fernando Case Rep Ophthalmol Med Case Report Purpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchanged for years. Results. In the first case, spectral-domain optical coherence tomography (SD-OCT) showed reduced foveal pit and continuity of inner retinal layers in the fovea. Photoreceptor layer had a normal thickness centrally. The foveal avascular zone (FAZ) was absent in the flourescein angiogram (FA). Fundus autofluorescence showed reduced foveal attenuation of autofluorescence. In the second patient, there was the same pattern in SD-OCT, with normal aspect in FA and only a slightly reduced foveal attenuation of autofluorescence. Conclusion. OCT, as a noninvasive and quick method, is helpful in the diagnosis of foveal hypoplasia. FA and fundus autofluorescence were less sensitive. Hindawi Publishing Corporation 2012 2012-07-31 /pmc/articles/PMC3415089/ /pubmed/22900218 http://dx.doi.org/10.1155/2012/864958 Text en Copyright © 2012 Ágata Mota et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mota, Ágata Fonseca, Sofia Carneiro, Ângela Magalhães, Augusto Brandão, Elisete Falcão-Reis, Fernando Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns |
title | Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns |
title_full | Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns |
title_fullStr | Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns |
title_full_unstemmed | Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns |
title_short | Isolated Foveal Hypoplasia: Tomographic, Angiographic and Autofluorescence Patterns |
title_sort | isolated foveal hypoplasia: tomographic, angiographic and autofluorescence patterns |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415089/ https://www.ncbi.nlm.nih.gov/pubmed/22900218 http://dx.doi.org/10.1155/2012/864958 |
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