Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods

A novel iron(III) complex [Fe(SF)](ClO(4))(3).2H(2)O; in which SF = N,N(0)-bis{5-[(triphenylphosphonium chloride)-methyl] salicylidene}-o-phenylenediamine) has been synthesized and characterized using different physicochemical methods. The binding of this complex with calf thymus (CT) DNA was invest...

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Autores principales: Shahabadi, Nahid, Ghasemian, Zeinab, Hadidi, Saba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415175/
https://www.ncbi.nlm.nih.gov/pubmed/22899896
http://dx.doi.org/10.1155/2012/126451
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author Shahabadi, Nahid
Ghasemian, Zeinab
Hadidi, Saba
author_facet Shahabadi, Nahid
Ghasemian, Zeinab
Hadidi, Saba
author_sort Shahabadi, Nahid
collection PubMed
description A novel iron(III) complex [Fe(SF)](ClO(4))(3).2H(2)O; in which SF = N,N(0)-bis{5-[(triphenylphosphonium chloride)-methyl] salicylidene}-o-phenylenediamine) has been synthesized and characterized using different physicochemical methods. The binding of this complex with calf thymus (CT) DNA was investigated by circular dichroism, absorption studies, emission spectroscopy, voltammetric studies, and viscosity measurements. The results showed that this complex can bind to DNA via external and groove binding modes.
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spelling pubmed-34151752012-08-16 Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods Shahabadi, Nahid Ghasemian, Zeinab Hadidi, Saba Bioinorg Chem Appl Research Article A novel iron(III) complex [Fe(SF)](ClO(4))(3).2H(2)O; in which SF = N,N(0)-bis{5-[(triphenylphosphonium chloride)-methyl] salicylidene}-o-phenylenediamine) has been synthesized and characterized using different physicochemical methods. The binding of this complex with calf thymus (CT) DNA was investigated by circular dichroism, absorption studies, emission spectroscopy, voltammetric studies, and viscosity measurements. The results showed that this complex can bind to DNA via external and groove binding modes. Hindawi Publishing Corporation 2012 2012-07-31 /pmc/articles/PMC3415175/ /pubmed/22899896 http://dx.doi.org/10.1155/2012/126451 Text en Copyright © 2012 Nahid Shahabadi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shahabadi, Nahid
Ghasemian, Zeinab
Hadidi, Saba
Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods
title Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods
title_full Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods
title_fullStr Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods
title_full_unstemmed Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods
title_short Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods
title_sort binding studies of a new water-soluble iron(iii) schiff base complex to dna using multispectroscopic methods
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415175/
https://www.ncbi.nlm.nih.gov/pubmed/22899896
http://dx.doi.org/10.1155/2012/126451
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