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Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers

Health-related physical fitness declines as the age advances. Oxidative stress is reported to contribute the crucial role on this phenomenon. This condition is also enhanced by antioxidant. Therefore, we aimed to determine the effect of Kaempferia parviflora, a plant reputed for antifatigue, longevi...

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Autores principales: Wattanathorn, Jintanaporn, Muchimapura, Supaporn, Tong-Un, Terdthai, Saenghong, Narisara, Thukhum-Mee, Wipawee, Sripanidkulchai, Bungorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415259/
https://www.ncbi.nlm.nih.gov/pubmed/22899957
http://dx.doi.org/10.1155/2012/732816
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author Wattanathorn, Jintanaporn
Muchimapura, Supaporn
Tong-Un, Terdthai
Saenghong, Narisara
Thukhum-Mee, Wipawee
Sripanidkulchai, Bungorn
author_facet Wattanathorn, Jintanaporn
Muchimapura, Supaporn
Tong-Un, Terdthai
Saenghong, Narisara
Thukhum-Mee, Wipawee
Sripanidkulchai, Bungorn
author_sort Wattanathorn, Jintanaporn
collection PubMed
description Health-related physical fitness declines as the age advances. Oxidative stress is reported to contribute the crucial role on this phenomenon. This condition is also enhanced by antioxidant. Therefore, we aimed to determine the effect of Kaempferia parviflora, a plant reputed for antifatigue, longevity promotion, and antioxidant effects, on health-related quality physical fitness and oxidative status of the healthy elderly volunteers. Total 45 subjects had been randomized to receive placebo or K. parviflora extract at doses of 25 or 90 mg once daily for 8 weeks. They were determined baseline data of physical performance using 30 sec chair stand test, hand grip test, 6 min walk test, and tandem test. Serum oxidative stress markers including malondialdehde (MDA) level and the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) were also assayed. All assessments were performed every 4 weeks throughout the 8-week study period. The results showed that K. parviflora increased performance in 30-second chair stand test and 6 min walk test together with the increased all scavenger enzymes activities and the decreased MDA level. Therefore, K. parviflora can enhance physical fitness partly via the decreased oxidative stress. In conclusion, K. parviflora is the potential health supplement for elderly. However, further study is required.
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spelling pubmed-34152592012-08-16 Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers Wattanathorn, Jintanaporn Muchimapura, Supaporn Tong-Un, Terdthai Saenghong, Narisara Thukhum-Mee, Wipawee Sripanidkulchai, Bungorn Evid Based Complement Alternat Med Research Article Health-related physical fitness declines as the age advances. Oxidative stress is reported to contribute the crucial role on this phenomenon. This condition is also enhanced by antioxidant. Therefore, we aimed to determine the effect of Kaempferia parviflora, a plant reputed for antifatigue, longevity promotion, and antioxidant effects, on health-related quality physical fitness and oxidative status of the healthy elderly volunteers. Total 45 subjects had been randomized to receive placebo or K. parviflora extract at doses of 25 or 90 mg once daily for 8 weeks. They were determined baseline data of physical performance using 30 sec chair stand test, hand grip test, 6 min walk test, and tandem test. Serum oxidative stress markers including malondialdehde (MDA) level and the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) were also assayed. All assessments were performed every 4 weeks throughout the 8-week study period. The results showed that K. parviflora increased performance in 30-second chair stand test and 6 min walk test together with the increased all scavenger enzymes activities and the decreased MDA level. Therefore, K. parviflora can enhance physical fitness partly via the decreased oxidative stress. In conclusion, K. parviflora is the potential health supplement for elderly. However, further study is required. Hindawi Publishing Corporation 2012 2012-07-31 /pmc/articles/PMC3415259/ /pubmed/22899957 http://dx.doi.org/10.1155/2012/732816 Text en Copyright © 2012 Jintanaporn Wattanathorn et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wattanathorn, Jintanaporn
Muchimapura, Supaporn
Tong-Un, Terdthai
Saenghong, Narisara
Thukhum-Mee, Wipawee
Sripanidkulchai, Bungorn
Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers
title Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers
title_full Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers
title_fullStr Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers
title_full_unstemmed Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers
title_short Positive Modulation Effect of 8-Week Consumption of Kaempferia parviflora on Health-Related Physical Fitness and Oxidative Status in Healthy Elderly Volunteers
title_sort positive modulation effect of 8-week consumption of kaempferia parviflora on health-related physical fitness and oxidative status in healthy elderly volunteers
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415259/
https://www.ncbi.nlm.nih.gov/pubmed/22899957
http://dx.doi.org/10.1155/2012/732816
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