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Synergistic effect of a combination of nanoparticulate Fe(3)O(4) and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells

BACKGROUND: The present study evaluated whether magnetic nanoparticles containing Fe(3)O(4) could enhance the activity of gambogic acid in human colon cancer cells, and explored the potential mechanisms involved. METHODS: Cytotoxicity was evaluated by MTT assay. The percentage of cells undergoing ap...

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Detalles Bibliográficos
Autores principales:	Fang, Lianghua, Chen, Baoan, Liu, Shenlin, Wang, Ruiping, Hu, Shouyou, Xia, Guohua, Tian, Yongli, Cai, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415324/ https://www.ncbi.nlm.nih.gov/pubmed/22888247 http://dx.doi.org/10.2147/IJN.S32475

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