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Mitochondrial Function in Permeabilized Cardiomyocytes Is Largely Preserved in the Senescent Rat Myocardium
The aging heart is characterized by a progressive decline in contractile function and diastolic relaxation. Amongst the factors implicated in these changes is a progressive replacement fibrosis secondary to cardiomyoctye death, oxidative damage, and energetic deficit, each of which may be secondary...
Autores principales: | Picard, Martin, Wright, Kathryn J., Ritchie, Darmyn, Thomas, Melissa M., Hepple, Russell T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415432/ https://www.ncbi.nlm.nih.gov/pubmed/22912774 http://dx.doi.org/10.1371/journal.pone.0043003 |
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