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Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes
Much emphasis has been placed on the identification, functional characterization, and therapeutic potential of somatic variants in tumor genomes. However, the majority of somatic variants lie outside coding regions and their role in cancer progression remains to be determined. In order to establish...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415438/ https://www.ncbi.nlm.nih.gov/pubmed/22912592 http://dx.doi.org/10.1371/journal.pgen.1002871 |