Cargando…

Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes

Much emphasis has been placed on the identification, functional characterization, and therapeutic potential of somatic variants in tumor genomes. However, the majority of somatic variants lie outside coding regions and their role in cancer progression remains to be determined. In order to establish...

Descripción completa

Detalles Bibliográficos
Autores principales: Parker, Stephen C. J., Gartner, Jared, Cardenas-Navia, Isabel, Wei, Xiaomu, Ozel Abaan, Hatice, Ajay, Subramanian S., Hansen, Nancy F., Song, Lingyun, Bhanot, Umesh K., Killian, J. Keith, Gindin, Yevgeniy, Walker, Robert L., Meltzer, Paul S., Mullikin, James C., Furey, Terrence S., Crawford, Gregory E., Rosenberg, Steven A., Samuels, Yardena, Margulies, Elliott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415438/
https://www.ncbi.nlm.nih.gov/pubmed/22912592
http://dx.doi.org/10.1371/journal.pgen.1002871