Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence

Paramyxovirus hemagglutinin-neuraminidase (HN) plays roles in viral entry and maturation, including binding to sialic acid receptors, activation of the F protein to drive membrane fusion, and enabling virion release during virus budding. HN can thereby directly influence virulence and in a subset of...

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Detalles Bibliográficos
Autores principales: Yuan, Ping, Paterson, Reay G., Leser, George P., Lamb, Robert A., Jardetzky, Theodore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415446/
https://www.ncbi.nlm.nih.gov/pubmed/22912577
http://dx.doi.org/10.1371/journal.ppat.1002855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415446/
https://www.ncbi.nlm.nih.gov/pubmed/22912577
http://dx.doi.org/10.1371/journal.ppat.1002855

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