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Components of a Fanconi-Like Pathway Control Pso2-Independent DNA Interstrand Crosslink Repair in Yeast

Fanconi anemia (FA) is a devastating genetic disease, associated with genomic instability and defects in DNA interstrand cross-link (ICL) repair. The FA repair pathway is not thought to be conserved in budding yeast, and although the yeast Mph1 helicase is a putative homolog of human FANCM, yeast ce...

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Detalles Bibliográficos
Autores principales: Ward, Thomas A., Dudášová, Zuzana, Sarkar, Sovan, Bhide, Mangesh R., Vlasáková, Danuša, Chovanec, Miroslav, McHugh, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415447/
https://www.ncbi.nlm.nih.gov/pubmed/22912599
http://dx.doi.org/10.1371/journal.pgen.1002884