HSV-1 Genome Subnuclear Positioning and Associations with Host-Cell PML-NBs and Centromeres Regulate LAT Locus Transcription during Latency in Neurons

Major human pathologies are caused by nuclear replicative viruses establishing life-long latent infection in their host. During latency the genomes of these viruses are intimately interacting with the cell nucleus environment. A hallmark of herpes simplex virus type 1 (HSV-1) latency establishment i...

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Detalles Bibliográficos
Autores principales: Catez, Frédéric, Picard, Christel, Held, Kathrin, Gross, Sylvain, Rousseau, Antoine, Theil, Diethilde, Sawtell, Nancy, Labetoulle, Marc, Lomonte, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415458/
https://www.ncbi.nlm.nih.gov/pubmed/22912575
http://dx.doi.org/10.1371/journal.ppat.1002852

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