Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”

An article by Polley and Fay in this issue of GENETICS provides an excellent opportunity to introduce or reinforce concepts of reverse genetics and RNA interference, suppressor screens, synthetic phenotypes, and phenocopy. Necessary background, explanations of these concepts, and a sample approach t...

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Detalles Bibliográficos
Autor principal: De Stasio, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415469/
https://www.ncbi.nlm.nih.gov/pubmed/22879405
http://dx.doi.org/10.1534/genetics.112.142943
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author De Stasio, Elizabeth A.
author_facet De Stasio, Elizabeth A.
author_sort De Stasio, Elizabeth A.
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description An article by Polley and Fay in this issue of GENETICS provides an excellent opportunity to introduce or reinforce concepts of reverse genetics and RNA interference, suppressor screens, synthetic phenotypes, and phenocopy. Necessary background, explanations of these concepts, and a sample approach to classroom use of the original article, including discussion questions, are provided.
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spelling pubmed-34154692013-08-01 Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans” De Stasio, Elizabeth A. Genetics Primer An article by Polley and Fay in this issue of GENETICS provides an excellent opportunity to introduce or reinforce concepts of reverse genetics and RNA interference, suppressor screens, synthetic phenotypes, and phenocopy. Necessary background, explanations of these concepts, and a sample approach to classroom use of the original article, including discussion questions, are provided. Genetics Society of America 2012-08 /pmc/articles/PMC3415469/ /pubmed/22879405 http://dx.doi.org/10.1534/genetics.112.142943 Text en Copyright © 2012 by the Genetics Society of America Available freely online through the author-supported open access option.
spellingShingle Primer
De Stasio, Elizabeth A.
Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
title Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
title_full Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
title_fullStr Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
title_full_unstemmed Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
title_short Suppressors, Screens, and Genes: An Educational Primer for Use with “A Network of Genes Antagonistic to the LIN-35 Retinoblastoma Protein of Caenorhabditis elegans”
title_sort suppressors, screens, and genes: an educational primer for use with “a network of genes antagonistic to the lin-35 retinoblastoma protein of caenorhabditis elegans”
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415469/
https://www.ncbi.nlm.nih.gov/pubmed/22879405
http://dx.doi.org/10.1534/genetics.112.142943
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