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Analysis of the -398C/T polymorphism in the perforin gene in oncohematological patients
BACKGROUND: Recently, single nucleotide polymorphisms (SNPs) were identified in the promoter region of the perforin gene (PRF1) and it was found that the -398T mutant allele is correlated with lower amounts of protein in circulating CD8(+) cytotoxic T lymphocytes. OBJECTIVE: The aim of this study wa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Associação Brasileira de Hematologia e Hemoterapia
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415754/ https://www.ncbi.nlm.nih.gov/pubmed/23049318 http://dx.doi.org/10.5581/1516-8484.20110076 |