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Evolution of the eukaryotic protein kinases as dynamic molecular switches

Protein kinases have evolved in eukaryotes to be highly dynamic molecular switches that regulate a plethora of biological processes. Two motifs, a dynamic activation segment and a GHI helical subdomain, distinguish the eukaryotic protein kinases (EPKs) from the more primitive eukaryotic-like kinases...

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Detalles Bibliográficos
Autores principales:	Taylor, Susan S., Keshwani, Malik M., Steichen, Jon M., Kornev, Alexandr P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415842/ https://www.ncbi.nlm.nih.gov/pubmed/22889904 http://dx.doi.org/10.1098/rstb.2012.0054

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