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Fluctuations of Fitness Distributions and the Rate of Muller’s Ratchet
The accumulation of deleterious mutations is driven by rare fluctuations that lead to the loss of all mutation free individuals, a process known as Muller’s ratchet. Even though Muller’s ratchet is a paradigmatic process in population genetics, a quantitative understanding of its rate is still lacki...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416007/ https://www.ncbi.nlm.nih.gov/pubmed/22649084 http://dx.doi.org/10.1534/genetics.112.141325 |