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Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges

Several psychiatric conditions, both internalizing and externalizing, have been documented in comorbidity with Asperger Syndrome (AS) and High Functioning Autism (HFA). In this review we examine the interplay between psychiatric comorbidities and AS/HFA. In particular, we will focus our attention on...

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Detalles Bibliográficos
Autores principales: Mazzone, Luigi, Ruta, Liliana, Reale, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416662/
https://www.ncbi.nlm.nih.gov/pubmed/22731684
http://dx.doi.org/10.1186/1744-859X-11-16
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author Mazzone, Luigi
Ruta, Liliana
Reale, Laura
author_facet Mazzone, Luigi
Ruta, Liliana
Reale, Laura
author_sort Mazzone, Luigi
collection PubMed
description Several psychiatric conditions, both internalizing and externalizing, have been documented in comorbidity with Asperger Syndrome (AS) and High Functioning Autism (HFA). In this review we examine the interplay between psychiatric comorbidities and AS/HFA. In particular, we will focus our attention on three main issues. First, we examine which psychiatric disorders are more frequently associated with AS/HFA. Second, we review which diagnostic tools are currently available for clinicians to investigate and diagnose the associated psychiatric disorders in individuals with AS/HFA. Third, we discuss the challenges that clinicians and researchers face in trying to determine whether the psychiatric symptoms are phenotypic manifestations of AS/HFA or rather they are the expression of a distinct, though comorbid, disorder. We will also consider the role played by the environment in the manifestation and interpretation of these symptoms. Finally, we will propose some strategies to try to address these issues, and we will discuss therapeutic implications.
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spelling pubmed-34166622012-08-11 Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges Mazzone, Luigi Ruta, Liliana Reale, Laura Ann Gen Psychiatry Review Several psychiatric conditions, both internalizing and externalizing, have been documented in comorbidity with Asperger Syndrome (AS) and High Functioning Autism (HFA). In this review we examine the interplay between psychiatric comorbidities and AS/HFA. In particular, we will focus our attention on three main issues. First, we examine which psychiatric disorders are more frequently associated with AS/HFA. Second, we review which diagnostic tools are currently available for clinicians to investigate and diagnose the associated psychiatric disorders in individuals with AS/HFA. Third, we discuss the challenges that clinicians and researchers face in trying to determine whether the psychiatric symptoms are phenotypic manifestations of AS/HFA or rather they are the expression of a distinct, though comorbid, disorder. We will also consider the role played by the environment in the manifestation and interpretation of these symptoms. Finally, we will propose some strategies to try to address these issues, and we will discuss therapeutic implications. BioMed Central 2012-06-25 /pmc/articles/PMC3416662/ /pubmed/22731684 http://dx.doi.org/10.1186/1744-859X-11-16 Text en Copyright ©2012 Mazzone et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Mazzone, Luigi
Ruta, Liliana
Reale, Laura
Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges
title Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges
title_full Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges
title_fullStr Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges
title_full_unstemmed Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges
title_short Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges
title_sort psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416662/
https://www.ncbi.nlm.nih.gov/pubmed/22731684
http://dx.doi.org/10.1186/1744-859X-11-16
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