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Exome sequencing generates high quality data in non-target regions

BACKGROUND: Exome sequencing using next-generation sequencing technologies is a cost efficient approach to selectively sequencing coding regions of human genome for detection of disease variants. A significant amount of DNA fragments from the capture process fall outside target regions, and sequence...

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Detalles Bibliográficos
Autores principales:	Guo, Yan, Long, Jirong, He, Jing, Li, Chung-I, Cai, Qiuyin, Shu, Xiao-Ou, Zheng, Wei, Li, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416685/ https://www.ncbi.nlm.nih.gov/pubmed/22607156 http://dx.doi.org/10.1186/1471-2164-13-194

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