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TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells

P73, one member of the tumor suppressor p53 family, shares highly structural and functional similarity to p53. Like p53, the transcriptionally active TAp73 can mediate cellular response to chemotherapeutic agents in human cancer cells by up-regulating the expressions of its pro-apoptotic target gene...

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Detalles Bibliográficos
Autores principales:	Zhang, Pingde, Liu, Stephanie Si, Ngan, Hextan Yuen Sheung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416758/ https://www.ncbi.nlm.nih.gov/pubmed/22900074 http://dx.doi.org/10.1371/journal.pone.0042985

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