Withaferin-A Reduces Type I Collagen Expression In Vitro and Inhibits Development of Myocardial Fibrosis In Vivo

Type I collagen is the most abundant protein in the human body. Its excessive synthesis results in fibrosis of various organs. Fibrosis is a major medical problem without an existing cure. Excessive synthesis of type I collagen in fibrosis is primarily due to stabilization of collagen mRNAs. We rece...

Descripción completa

Detalles Bibliográficos
Autores principales: Challa, Azariyas A., Vukmirovic, Milica, Blackmon, John, Stefanovic, Branko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416765/
https://www.ncbi.nlm.nih.gov/pubmed/22900077
http://dx.doi.org/10.1371/journal.pone.0042989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416765/
https://www.ncbi.nlm.nih.gov/pubmed/22900077
http://dx.doi.org/10.1371/journal.pone.0042989

Ejemplares similares