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Leishmania Exosomes Deliver Preemptive Strikes to Create an Environment Permissive for Early Infection

Herein, we review evidence supporting a role for Leishmania exosomes during early infection. We suggest a model in which Leishmania secreted microvesicles released into the extracellular milieu deliver effector cargo to host target cells. This cargo mediates immunosuppression and functionally primes...

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Detalles Bibliográficos
Autores principales: Silverman, Judith Maxwell, Reiner, Neil E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417360/
https://www.ncbi.nlm.nih.gov/pubmed/22919591
http://dx.doi.org/10.3389/fcimb.2011.00026