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Leishmania Exosomes Deliver Preemptive Strikes to Create an Environment Permissive for Early Infection
Herein, we review evidence supporting a role for Leishmania exosomes during early infection. We suggest a model in which Leishmania secreted microvesicles released into the extracellular milieu deliver effector cargo to host target cells. This cargo mediates immunosuppression and functionally primes...
Autores principales: | Silverman, Judith Maxwell, Reiner, Neil E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417360/ https://www.ncbi.nlm.nih.gov/pubmed/22919591 http://dx.doi.org/10.3389/fcimb.2011.00026 |
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