Broad segmental progeroid changes in short-lived Ercc1(−/Δ7) mice

Genome maintenance is considered a prime longevity assurance mechanism as apparent from many progeroid human syndromes that are caused by genome maintenance defects. The ERCC1 protein is involved in three genome maintenance systems: nucleotide excision repair, interstrand cross-link repair, and homo...

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Detalles Bibliográficos
Autores principales: Dollé, Martijn E.T., Kuiper, Raoul V., Roodbergen, Marianne, Robinson, Joke, de Vlugt, Sisca, Wijnhoven, Susan W.P., Beems, Rudolf B., de la Fonteyne, Liset, de With, Piet, van der Pluijm, Ingrid, Niedernhofer, Laura J., Hasty, Paul, Vijg, Jan, Hoeijmakers, Jan H.J., van Steeg, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417667/
https://www.ncbi.nlm.nih.gov/pubmed/22953029
http://dx.doi.org/10.3402/pba.v1i0.7219

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