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The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease characterized by the loss of motor neurons. Despite substantial research, the causes of ALS remain unclear. Glycoprotein nonmetastatic melanoma protein B (GPNMB) was identified as an ALS-related factor using DNA...

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Detalles Bibliográficos
Autores principales: Tanaka, Hirotaka, Shimazawa, Masamitsu, Kimura, Masataka, Takata, Masafumi, Tsuruma, Kazuhiro, Yamada, Mitsunori, Takahashi, Hitoshi, Hozumi, Isao, Niwa, Jun-ichi, Iguchi, Yohei, Nikawa, Takeshi, Sobue, Gen, Inuzuka, Takashi, Hara, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417778/
https://www.ncbi.nlm.nih.gov/pubmed/22891158
http://dx.doi.org/10.1038/srep00573