Application of nanogel systems in the administration of local anesthetics

Nanogels are robust nanoparticles that could be used to deliver active drug compounds in controlled drug delivery applications. This review discusses the design, synthesis, loading, and release of local anesthetics using polymeric nanoparticles produced via various types of polymerization techniques...

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Detalles Bibliográficos
Autores principales: Tan, Jeremy PK, Tan, Maureen BH, Tam, Michael KC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417954/
https://www.ncbi.nlm.nih.gov/pubmed/22915875
http://dx.doi.org/10.2147/LRA.S7977
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author Tan, Jeremy PK
Tan, Maureen BH
Tam, Michael KC
author_facet Tan, Jeremy PK
Tan, Maureen BH
Tam, Michael KC
author_sort Tan, Jeremy PK
collection PubMed
description Nanogels are robust nanoparticles that could be used to deliver active drug compounds in controlled drug delivery applications. This review discusses the design, synthesis, loading, and release of local anesthetics using polymeric nanoparticles produced via various types of polymerization techniques. The strategy of using layer-by-layer approach to control the burst release of procaine hydrochloride (PrHy; a local anesthetic drug of the amino ester group) is described and discussed.
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spelling pubmed-34179542012-08-22 Application of nanogel systems in the administration of local anesthetics Tan, Jeremy PK Tan, Maureen BH Tam, Michael KC Local Reg Anesth Review Nanogels are robust nanoparticles that could be used to deliver active drug compounds in controlled drug delivery applications. This review discusses the design, synthesis, loading, and release of local anesthetics using polymeric nanoparticles produced via various types of polymerization techniques. The strategy of using layer-by-layer approach to control the burst release of procaine hydrochloride (PrHy; a local anesthetic drug of the amino ester group) is described and discussed. Dove Medical Press 2010-09-01 /pmc/articles/PMC3417954/ /pubmed/22915875 http://dx.doi.org/10.2147/LRA.S7977 Text en © 2010 Tan et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Tan, Jeremy PK
Tan, Maureen BH
Tam, Michael KC
Application of nanogel systems in the administration of local anesthetics
title Application of nanogel systems in the administration of local anesthetics
title_full Application of nanogel systems in the administration of local anesthetics
title_fullStr Application of nanogel systems in the administration of local anesthetics
title_full_unstemmed Application of nanogel systems in the administration of local anesthetics
title_short Application of nanogel systems in the administration of local anesthetics
title_sort application of nanogel systems in the administration of local anesthetics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417954/
https://www.ncbi.nlm.nih.gov/pubmed/22915875
http://dx.doi.org/10.2147/LRA.S7977
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AT tanmaureenbh applicationofnanogelsystemsintheadministrationoflocalanesthetics
AT tammichaelkc applicationofnanogelsystemsintheadministrationoflocalanesthetics

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