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PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells

BACKGROUND: Effective cancer chemotherapy remains an important issue in cancer treatment, and signal transducer and activator of transcription-3 (Stat3) activation leads to cellular resistance of anticancer agents. Polymers are ideal vectors to carry both chemotherapeutics and small interfering ribo...

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Detalles Bibliográficos
Autores principales: Su, Wen-Pin, Cheng, Fong-Yu, Shieh, Dar-Bin, Yeh, Chen-Sheng, Su, Wu-Chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418083/
https://www.ncbi.nlm.nih.gov/pubmed/22904633
http://dx.doi.org/10.2147/IJN.S33666