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Improved biological properties and hypouricemic effects of uricase from Candida utilis loaded in novel alkaline enzymosomes
OBJECTIVE: Previous studies on various enzymosomes (functional lipid vesicles encapsulating an enzyme) have been mostly carried out in vitro and have focused on preserving catalytic activity and improving the stability of the enzyme. Until now, few studies have focused on their in vivo fate. Similar...
Autores principales: | Tan, Qun-You, Zhang, Jing-Qing, Wang, Na, Yang, Hong, Li, Xiaoling, Xiong, Hua-Rong, Wu, Jian-Yong, Zhao, Chun-Jing, Wang, Hong, Yin, Hua-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418170/ https://www.ncbi.nlm.nih.gov/pubmed/22915844 http://dx.doi.org/10.2147/IJN.S33835 |
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