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Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus

BACKGROUND: Neuroinflammation plays an important role in cerebral ischemia/reperfusion (I/R) injury. The P2X7 receptor (P2X7R) has been reported to be involved in the inflammatory response of many central nervous system diseases. However, the role of P2X7Rs in transient global cerebral I/R injury re...

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Detalles Bibliográficos
Autores principales: Chu, Ketan, Yin, Bo, Wang, Jingye, Peng, Guoping, Liang, Hui, Xu, Ziqi, Du, Yue, Fang, Marong, Xia, Qiang, Luo, Benyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418181/
https://www.ncbi.nlm.nih.gov/pubmed/22513224
http://dx.doi.org/10.1186/1742-2094-9-69

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