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The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner
BACKGROUND: CTCF is a highly conserved and essential zinc finger protein expressed in virtually all cell types. In conjunction with cohesin, it organizes chromatin into loops, thereby regulating gene expression and epigenetic events. The function of CTCFL or BORIS, the testis-specific paralog of CTC...
Autores principales: | Sleutels, Frank, Soochit, Widia, Bartkuhn, Marek, Heath, Helen, Dienstbach, Sven, Bergmaier, Philipp, Franke, Vedran, Rosa-Garrido, Manuel, van de Nobelen, Suzanne, Caesar, Lisa, van der Reijden, Michael, Bryne, Jan Christian, van IJcken, Wilfred, Grootegoed, J Anton, Delgado, M Dolores, Lenhard, Boris, Renkawitz, Rainer, Grosveld, Frank, Galjart, Niels |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418201/ https://www.ncbi.nlm.nih.gov/pubmed/22709888 http://dx.doi.org/10.1186/1756-8935-5-8 |
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