Human Milk IgGs Contain Various Combinations of Different Antigen-Binding Sites Resulting in Multiple Variants of their Bispecificity

In the classic paradigm, immunoglobulins represent products of clonal B cell populations, each producing antibodies (Abs) recognizing a single antigen. There is a common belief that IgGs in mammalian biological fluids are monovalent molecules having stable structures and two identical antigen-bindin...

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Detalles Bibliográficos
Autores principales: Sedykh, Sergey E., Buneva, Valentina N., Nevinsky, Georgy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418227/
https://www.ncbi.nlm.nih.gov/pubmed/22912765
http://dx.doi.org/10.1371/journal.pone.0042942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418227/
https://www.ncbi.nlm.nih.gov/pubmed/22912765
http://dx.doi.org/10.1371/journal.pone.0042942

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