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Human Milk IgGs Contain Various Combinations of Different Antigen-Binding Sites Resulting in Multiple Variants of their Bispecificity
In the classic paradigm, immunoglobulins represent products of clonal B cell populations, each producing antibodies (Abs) recognizing a single antigen. There is a common belief that IgGs in mammalian biological fluids are monovalent molecules having stable structures and two identical antigen-bindin...
Autores principales: | Sedykh, Sergey E., Buneva, Valentina N., Nevinsky, Georgy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418227/ https://www.ncbi.nlm.nih.gov/pubmed/22912765 http://dx.doi.org/10.1371/journal.pone.0042942 |
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