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Characterization of the Host Factors Required for Hepadnavirus Covalently Closed Circular (ccc) DNA Formation
Synthesis of the covalently closed circular (ccc) DNA is a critical, but not well-understood step in the life cycle of hepadnaviruses. Our previous studies favor a model that removal of genome-linked viral DNA polymerase occurs in the cytoplasm and the resulting deproteinized relaxed circular DNA (D...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418247/ https://www.ncbi.nlm.nih.gov/pubmed/22912842 http://dx.doi.org/10.1371/journal.pone.0043270 |