Binding of Translationally Controlled Tumour Protein to the N-Terminal Domain of HDM2 Is Inhibited by Nutlin-3

Translationally Controlled Tumour Protein (TCTP), a highly conserved protein present in all eukaryotic organisms, has a number of intracellular and extracellular functions including an anti-apoptotic role. TCTP was recently shown to interact with both p53 and HDM2, inhibiting auto-ubiquitination of...

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Detalles Bibliográficos
Autores principales: Funston, Garth, Goh, Walter, Wei, Siau Jia, Tng, Quah Soo, Brown, Christopher, Jiah Tong, Loh, Verma, Chandra, Lane, David, Ghadessy, Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418249/
https://www.ncbi.nlm.nih.gov/pubmed/22912717
http://dx.doi.org/10.1371/journal.pone.0042642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418249/
https://www.ncbi.nlm.nih.gov/pubmed/22912717
http://dx.doi.org/10.1371/journal.pone.0042642

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