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Heparin Inhibits Hepatocyte Growth Factor Induced Motility and Invasion of Hepatocellular Carcinoma Cells through Early Growth Response Protein 1
The Hepatocyte Growth Factor (HGF)/c-Met signaling pathway regulates hepatocyte proliferation, and pathway aberrations are implicated in the invasive and metastatic behaviors of hepatocellular carcinoma (HCC). In addition to c-Met, heparin acts as a co-receptor to modulate pathway activity. Recently...
Autores principales: | Ozen, Evin, Gozukizil, Aysim, Erdal, Esra, Uren, Aykut, Bottaro, Donald P., Atabey, Nese |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418296/ https://www.ncbi.nlm.nih.gov/pubmed/22912725 http://dx.doi.org/10.1371/journal.pone.0042717 |
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